Ethan Dmitrovsky, MD, Oral History Interview, March 3, 2015
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Major Topics Covered:
- Personal and educational background; overseas experience and inspiration
- Research: cell differentiation; retinoids in leukemic differentiation; lung cancer studies
- The Role of the Provost; personal goals; institutional mandate; detailed of plans
- MD Anderson’s ten-year strategic plan
- Research in an environment of changing economics and health care delivery
Chapter 01: An Early Desire to Be a Physician and Focus on Difficult Illnesses
Chapter 02: College Influences: A Research Project, a Book, and Working as an Orderly
Chapter 03: Medical School and a Life-Changing Experience as a Physician Volunteer Near the Cambodia-Thailand Border
Chapter 04: A Fellowship and a Risky and Successful Study of Cell Differentiation
Chapter 05: A Faculty Position and a New Laboratory to Study the Role of Retinoids in Leukemic Differentiation
Chapter 06: Shifting Focus to Lung Cancer
Chapter 07: Coming to MD Anderson to Have a Broader Impact on Health
Chapter 08: Views on MD Anderson's 10-Year Strategic Plan and the Role of the Provost
Chapter 09: Creating a New Way of Conducting Research and Caring for Patients in a Changing Environment
The Historical Resources Center, Research Medical Library, The University of Texas Cancer Center
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University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Texas System. M.D. Anderson Cancer Center, M.D. Anderson Hospital and Tumor Institute at Houston, University of Texas M.D. Anderson Cancer Center, M.D. Anderson Hospital and Tumor Institute
History of Science, Technology, and Medicine | Oncology | Oral History
Dmitrovsky, Ethan MD and Rosolowski, Tacey A. PhD, "Ethan Dmitrovsky, MD, Oral History Interview, March 3, 2015" (2015). Interview Sessions. 102.
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About the Interview
About the Interview Subject:
Ethan Dmitrovsky, MD came to MD Anderson in 2013 to serve as the institution’s Provost and Executive Vice President. He has a faculty appointment in the Department of Thoracic/Head and Neck Medical Oncology in the Division of Cancer Medicine.
Dr. Dmitrovsky’s translational research areas include: retinoid differentiation-based therapy for acute promyelocytic leukemia (APL); developed the molecular genetic test used to detect the PML/RARalpha transcript from the APL t(15;17) rearrangement; retinoid mechanisms leading to cell cycle arrest and repair of DNA damage in normal/malignant lung epithelial cells; engineered transgenic mouse models that express wild-type or proteasomal degradation-resistant cyclin E species in the lung; derived lung cancer cell lines leading to a new model to assess activity of lung cancer therapy and chemopreventive agents (antineoplastics).