Effects of PARP inhibitors, SGLT2 inhibitors, and Colchicine on Doxorubicin-induced Premature Senescence Induced-Phenotype

Authors

Michelle Xiaoyi Lu, John A. Burns School of MedicineFollow
Jun-ichi Abe, The University of Texas MD Anderson Cancer Center
Sivareddy Kotla, The University of Texas MD Anderson Cancer Center
Kyung Ae Ko, The University of Texas MD Anderson Cancer Center
Samanthapudi K. Venkatasubrahman, The University of Texas MD Anderson Cancer Center

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Keywords

cardiotoxicity, premature senescence induced pheotype, SGLT2 inhibitor, Colchicine, Chemotherapy-induced cardiotoxicity, PARP inhibitor, Olaparib, doxorubicin, mitochondrial telomere damage

Program Affiliation

First Year Medical Student Program

Recommended Citation

Lu, Michelle Xiaoyi; Abe, Jun-ichi; Kotla, Sivareddy; Ko, Kyung Ae; and Venkatasubrahman, Samanthapudi K., "Effects of PARP inhibitors, SGLT2 inhibitors, and Colchicine on Doxorubicin-induced Premature Senescence Induced-Phenotype" (2022). Summer Experience 2022. 74.
https://openworks.mdanderson.org/sumexp22/74