Unleashing the Immune System to Develop Therapeutic Strategies
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Long-term avasimibe treatment abolishes the breast cancer preventative efficacy of statin in a spontaneous mouse model of breast cancer
Rhea Bhala, Anjana Bhardwaj, Alexander Koh, Zhenlin Ju, Jing Wang, and Isabelle Bedrosian
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DPY30 loss leads to DNA re-replication and immunoediting in pancreatic ductal adenocarcinoma
Francesca Citron, Luigi Perelli, Yanshuo Chu, Sanjana Srinivasan, I-Lin Ho, Er-Yen Yen, Rutvi Shah, Sergio Attanasio, Luis Alejandro Castillo Montanez, Mauro Di Pilato, Shan Jiang, Sisi Gao, Angela K. Deem, Giannicola Genovese, Virginia Giuliani, Linghua Wang, Alessandro Carugo, Andrea Viale, and Giulio Draetta
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Galectin-3 synergizes with CD47 to Suppress Phagocytosis and T cell immunity in Peritoneal Metastases of Gastric Adenocarcinoma
Yibo Fan, Shilpa S. Dhar, Jiankang Jin, Xiaodan Yao, Ruiping Wang, Ailing W. Scott, Melissa Pool Pizzi, Lang Ma, Shan Shao, Matheus Sewastjanow Da Silva, Jingjing Wu, Namita Shanbhag, Linghua Wang, Michael Curran, Shumei Song, and Jaffer A. Ajani
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Loss of BRD7 promotes breast cancer lung metastasis by reprogramming the tumor immune microenvironment
Jayanta Mondal; Junfeng Zhang; Filippo G. Giancotti MD, PhD; and Jason Huse
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Characterization of Altered immunity in Anaplastic Thyroid Cancer
Rim Ouni, Ying Henderson, Yunyun Chen, Naimah Turner, William Padron, Ali Dadbin, Elena McBeath Fujiwara, Jennifer R. Wang, Maria Cabanillas, Ramona Dadu, Marie-Claude Hofmann, MarK E. Zafereo, Sang Taek Kim, Stephen Lai, and Roza Nurieva
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IL-6 contributes to the suppression of T and NK cell anti-tumor activity in EGFR-mutant NSCLC
Sonia A. Patel, Monique B. Nilsson, Yan Yang, XIaoxing Yu, Fahao Zhang, Alissa Poteete, Xiaoyang Ren, Xiuning Le, Li Shen, Jing Wang, and John Heymach
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Targeting immunosuppressive classical monocytes prevents immunotherapy resistance
B. Leticia Rodriguez, Limo Chen, Yanli Li, Shucheng Miao, David H. Peng, Jared Fradette, Lixia Diao, Jessica Marie Konen, Aparna Padhye, Laura Gibson, Joshua K. Ochieng, Xiaofei Zhou PhD, Jing Wang, and Don Gibbons
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Characterization of T/B cell antigen specific-engineered tumors for studying T cell and GC B cell function in a murine model of NSCLC
Armando J. Ruiz-Justiz; Mona Yazdani; Xin Sun; Lili Chen; Michael Wang; John Le; Haiping Guo; Can Cui; Kelli Cannolly; Aya Tal; Wei Hu MD, PhD; Nikhil Joshi PhD; and Tina Cascone MD, PhD
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Cancer testis antigen and interleukin expression correlates with survival in small bowel neuroendocrine tumors
Y David Seo, Russell G. Witt, Samuel Cass, Rossana Lazcano, Courtney Hudgens, Khalida Wani, Sharia Hernandez, Daniel Halperin, Alexander Lazar, Jennifer Wargo, Jeannelyn S. Estrella, and Jessica E. Maxwell
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Determine the relevance of HPV-specific T-cells in the immune response against the HPV-positive cancers
Klaudia A. Szymonowicz, Emily G. Bontekoe, Bo Jiang, Alexa J. Halliday, Maura Gillison L, and Nils-Petter Rudqvist
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Exploring anti-PD-1 resistance mechanisms for therapeutic targeting in NSCLC
Haoyi Wu, Jessica Marie Konen, Leticia Rodriguez, Yanhua Tian, Susan Tsang, Jared Fradette, Laura Gibson, and Don Gibbons
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Validating DLL3-targeting CAR T in small cell lung cancer
Bingnan Zhang, Yan Yang, Allison Stewart, Runsheng Wang, Kavya Ramkumar, Robert Cardnell, Azusa Tanimoto, Ali Ibraham, Kyle Concannon, Ben Morris, Lixia Diao, Qi Wang, Jing Wang, Carl Gay, John Heymach, and Lauren A. Byers
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Efficacy and immune modulation of KRAS G12C inhibitor sotorasib in murine KRAS G12C mutant non-small cell lung cancers with major co-occurring genomic alterations
Teng Zhou, Minh Truong Do, Haniel Araujo, Richard Lee, and Ferdinandos Skoulidis
