Abstract
Purpose To evaluate the impact of magnetic resonance-guided linear accelerator (MR-Linac) technology on treatment precision, clinical outcomes, and operational challenges in prostate cancer radiotherapy.
Method A systematic literature review was conducted using PubMed, Scopus, and Google Scholar to identify peer-reviewed studies published between 2018 and 2026. Eligible studies evaluated MR-Linac technology for prostate cancer and reported outcomes related to treatment precision, toxicity, workflow, and clinical effectiveness.
Results Three primary themes emerged: (a) improved treatment precision through superior soft tissue visualization, real-time target tracking, and adaptive radiotherapy; (b) improved clinical outcomes characterized by reduced radiation exposure to organs at risk, decreased treatment-related toxicity, and favorable tumor control; and (c) implementation challenges, including longer treatment times, workflow complexity, and patient eligibility limitations.
Discussion MR-Linac technology enhances the precision of prostate cancer radiotherapy by allowing clinicians to adapt treatment in real time while minimizing radiation exposure to surrounding healthy tissues. These capabilities support personalized treatment approaches and may improve patient outcomes. However, successful implementation requires addressing operational challenges related to workflow efficiency, staff training, treatment duration, and patient selection. Additional prospective studies are needed to evaluate long-term clinical outcomes and optimize integration into routine practice.
Conclusion MR-Linac represents a significant advancement in prostate cancer radiotherapy by improving treatment precision while reducing normal tissue toxicity. Continued research and technological development are needed to support broader clinical adoption.
DOI
https://doi.org/10.52519/00272
Graduation Date
Summer 8-7-2026
Document Type
Poster
Degree Name
Master of Science in Radiologic Science
Program
The School of Health Professions
Faculty Advisor
Kevin R. Clark
Director, Graduate Program
William A. Undie
Dean
Kimberly Hoggatt Krumwiede
Recommended Citation
Tran, A. P. Impact of MR-Linac Technology on Prostate Cancer Treatment Outcomes. [poster]. University of Texas MD Anderson Cancer Center; 2026. https://doi.org/10.52519/00272
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