Other
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Aerobic exercise impacts the tumor microenvironment by altering CAF abundance and composition in pancreatic cancer
Riccardo Ballarò, Sumedha Pareek, Jonghae Lee, Hetal Patel, and Keri Schadler
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Ether phospholipids metabolism is a latent vulnerability for pancreatic cancer resistance
Ziheng Chen; I-Lin Ho; Liang Yan; Shujuan Chen; Melinda Soeung; Johnathon L. Rose; Sanjana Srinivasan; Andrea Viale; Alessandro Carugo; Giannicola Genovese; Wantong Yao MD, PhD; Ningping Feng; Jason P. Gay; Joeeph Marszalek; Haoqiang Ying; and Giulio Draetta
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Transcriptional profiling and consensus molecular subtype (CMS) assignment to understand response and resistance to anti-EGFR therapy in colorectal cancer
Saikat Chowdhury, Ria Gupta, Valsala Haridas, Mohammad Zeineddine, Scott Kopetz, and John Paul Shen
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Organoid Imaging Strategies for Accelerating Translational Research
Charles Deckard III, Joseph R. Daniele, Dmitriy Loza, Vandhana Ramamoorthy, Kuo-Shun Hsu, Mikhila Mahendra, Ben Bivona, Ningping Feng, Henry Lyu, Jing Han, and Joe Marszalek
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Retrospective Determination of Prognostic Factors in BRAF-V600E Melanoma Brain Metastases
Lily G. Erickson, Sahana Ramaswamy, Sherise D. Ferguson, James P. Long, Hussein Tawbi, Merve Hasanov, Alicia B. Davies, Elizabeth Sirmans, Chantal Saberian, Eliza L. Posada, Jared Malke, Lauren Haydu, and Caroline Chung
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Comparative Transcriptomic Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors
Eleonora Khlebus, Veena K. Vuttaradhi, Thomas Welte, Namrata Khurana, Joseph Celestino, Hannah C. Beird, Curtis Gumbs, Latasha Little, Tri Nguyen, Barrett Lawson, Russell R. Broaddus, David M. Gershenson MD, Andrew Futreal, and R Tyler Hillman
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Role of HIF2 signaling in small intestine regeneration after radiation injury
Neeraj Kumari, Maya Ferrell, Carolina Garcia-Garcia, and Cullen M. Taniguchi
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Tackling Healthcare Inequities: Development & Implementation of a Virtual Platform to Improve Global Access to Oncology Education
Yan Leyfman, William B. Wilkerson, Shubhadarshini G. Pawar, Muskan Joshi, Gayathri Pramil Menon, Alexandra van de Kieft, and Chandler H. Park
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Histone demethylase KDM5D drives sex-specific differences in colorectal cancer
Jiexi Li; Zhengdao Lan; Wenting Liao; James W. Horner; Xueping Xu; Jielin Liu; Yohei Yoshihama; Shan Jiang; Hong Seok Shim; Max Slotnik; Chang-Jiun Wu; Kenneth Dunner, Jr.; Rumi Lee; Isha Khanduri; Christopher Terranova; Kadir Caner Akdemir; Deepavali Chakravarti; Kyle LaBella; Wen-Hao Hsu; Denise J. Spring; Y. Alan Wang; and Ronald A. DePinho
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Targeting histone lysine demethylase KDM4A in Aggressive Variant Prostate Cancer
Celia Sze Ling Mak, Ming Zhu, Xin Liang, Feng Wang, Anh G. Hoang, Xinzhi Song, Peter Shepherd, Derek Liang, Jessica Suh, Jiwon Park, Miao Zhang, Eric Metzger, Roland Schule, Abhinav K. Jain, Ellen Karasik, Barbara A. Foster, Min Gyu Lee, Paul Corn, Christopher J. Logothetis MD, Ana Aparicio, Nora Navone, Patricia Troncoso, Jianhua Zhang, Sue-Hwa Lin, and Guocan Wang
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Enhanced TP53 Reactivation Disrupts MYC Transcriptional Program and Overcomes Venetoclax Resistance in Acute Myeloid Leukemias
Yuki Nishida MD, PhD; Jo Ishizawa; Edward Ayoub PhD; Tallie Patsilevas; Lauren Ostermann; Rafael Heinz Montoya; Muharrem Muftuoglu; Vivian R. Ruvolo; Po Yee Mak; Wenjing Tao; Bing Z. Carter; Darah A. Scruggs; Kensuke Kojima; Naval Daver; Takahiko Seki; Sharon Shacham; Marina Konopleva MD, PhD; and Michael Andreeff MD, PhD
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C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill in vitro and in vivo in Acute Myeloid Leukemia and Lymphomas
Yuki Nishida MD, PhD; Darah A. Scruggs; Edward Ayoub PhD; Tallie Patsilevas; Lauren Ostermann; Vivian R. Ruvolo; Po Yee Mak; Bing Z. Carter; Steffen Boettcher; Abhishek Maiti; Qianxiang Zhou; Zhaohui Yang; Honghua Yan; Liandong Ma; and Michael Andreeff MD, PhD
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K811 acetylation regulates ZEB1 dimerization, protein stability, and NuRD complex interactions to promote lung adenocarcinoma progression and metastasis
Mabel Perez-Oquendo, Roxsan Manshouri, Jared J. Fradette, and Don Gibbons
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Characterizing the role of chromosome 3 copy-loss in driving late-stage Uveal Melanoma
Johnathon L. Rose, Sanjana Srinivasan, and The Rare Tumor Initiative Team and TRACTION Platform
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Development of a Novel Combination Therapy targeting MET and LGR5 to overcome Colorectal Cancer Resistance
Shraddha Subramanian, Tressie Posey, Joan Jacob, and Kendra S. Carmon
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Targeting DNA2 Overcomes Metabolic Reprogramming in 1q21 Multiple Myeloma
Natthakan Thongon; Feiyang Ma; Matteo Marchesini; Jintan Liu; Natalia Baran; Pamela Lockyer; Andrea Santoni; Christopher Jackson; Ashley Rose; Irene Ganan-Gomez; Vera Adema; Valentina Marchica; Paola Storti; Nicola Giuliani; Guillermo Montalban-Bravo; Yun Qing; Min Ha; Rodrigo Fonseca; Caleb Class; Lin Tan; Rashmi Kanagal-Shamanna; David Berrios Nolasco; Marina Konopleva MD, PhD; Philip L. Lorenzi; Guillermo Garcia-Manero MD; Elisabet Manasanch; Marta Chesi; and Simona Colla
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Unraveling the Biology of Desmoplastic Small Round Cell Tumor
Danh D. Truong, Emre Arslan, Margarita Divenko, Sandhya Krishnan, Alexander Lazar, Kunal Rai, and Joseph Ludwig
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Lysosomal transmembrane protein TMEM106B alters TFEB signaling and the tumor immune microenvironment
Amanda N. Warner, Samrat T. Kundu, Rakhee Bajaj, Bertha Leticia Rodriguez, and Don Gibbons
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Targeting Medium-Chain Acyl-CoA Dehydrogenase for Glioblastoma
Fei Yu, Paul Leonard, Matthew Hamilton, Francesca Puca, Nhung Pham, Norma Rogers, Fernando Alvarez, C Rodriguez, Vinay Nair, Narahari Akkaladevi, Roopa Thapar, Scott Vaccaro, Andrea Mendiola, Quanyun Xu, Mary Geck Do, Jason Cross, Mick Soth, Yongying Jiang, Giulio Draetta, and Philip Jones
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Yap1 Hydroxylation Suppress Prostate Cancer Metastasis
Ming Zhu, Ruiqing Peng, Xin Liang, Zhengdao Lan, Ming Tang, Pingping Hou, Jian H. Song, Celia Sze Ling Mak, Jiwon Park, Shui-Er Zheng, Ailing Huang, Xingdi Ma, Ruidong Chen, Qing Chang, Christopher J. Logothetis MD, Abhinav K. Jain, Sue-Hwa Lin, Hiroyuki Katayama, Samir Hanash, and Guocan Wang