Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1 Mutant Myelodysplastic Syndromes With Ringed Sideroblasts

Authors

Vera Adema, The University of Texas MD Anderson Cancer Center
Feiyang Ma
Rashmi Kanagal-Shamanna, The University of Texas MD Anderson Cancer Center
Natthakan Thongon, The University of Texas MD Anderson Cancer Center
Guillermo Montalban-Bravo, The University of Texas MD Anderson Cancer Center
Hui Yang, The University of Texas MD Anderson Cancer Center
Scott A. Peslak
Feng Wang
Pamela Acha
Francesc Sole
Pamela Lockyer, The University of Texas MD Anderson Cancer Center
Margherita Cassari
Jaroslaw P. Maciejewski
Valeria Visconte
Irene Ganan-Gomez, The University of Texas MD Anderson Cancer Center
Yuanbin Song
Carlos Bueso-Ramos, The University of Texas MD Anderson Cancer Center
Matteo Pellegrini
Tuyet M. Tan
Rafael Bejar
Jennifer S. Carew
Stephanie Halene
Valeria Santini
Gheath Al Atrash, The University of Texas MD Anderson Cancer Center
Karen Clise-Dwyer, The University of Texas MD Anderson Cancer Center
Guillermo Garcia-Manero MD, The University of Texas MD Anderson Cancer Center
Gerd A. Blobel
Simona Colla, The University of Texas MD Anderson Cancer Center

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Abstract

View full abstract

DOI

https://doi.org/10.52519/00041

Publication Date

2022

Department

Leukemia

Research Category

The Patient is the Focus

Recommended Citation

Adema, Vera; Ma, Feiyang; Kanagal-Shamanna, Rashmi; Thongon, Natthakan; Montalban-Bravo, Guillermo; Yang, Hui; Peslak, Scott A.; Wang, Feng; Acha, Pamela; Sole, Francesc; Lockyer, Pamela; Cassari, Margherita; Maciejewski, Jaroslaw P.; Visconte, Valeria; Ganan-Gomez, Irene; Song, Yuanbin; Bueso-Ramos, Carlos; Pellegrini, Matteo; Tan, Tuyet M.; Bejar, Rafael; Carew, Jennifer S.; Halene, Stephanie; Santini, Valeria; Al Atrash, Gheath; Clise-Dwyer, Karen; Garcia-Manero, Guillermo MD; Blobel, Gerd A.; and Colla, Simona, "Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1 Mutant Myelodysplastic Syndromes With Ringed Sideroblasts" (2022). Leading Edge of Cancer Research Symposium. 26.
doi:https://doi.org/10.52519/00041