Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

Authors

Yifan Zhou, The University of Texas MD Anderson Cancer Center
Yusra B. Medik, The University of Texas MD Anderson Cancer Center
Bhakti Patel, The University of Texas MD Anderson Cancer Center
Daniel B. Zamler, The University of Texas MD Anderson Cancer Center
Sijie Chen, Tsinghua University
Thomas Chapman, The University of Texas MD Anderson Cancer Center
Sarah Schneider, The University of Texas MD Anderson Cancer Center
Elizabeth M. Park, The University of Texas MD Anderson Cancer Center
Rachel Babcock, The University of Texas MD Anderson Cancer Center
Taylor Chrisikos, The University of Texas MD Anderson Cancer Center
Laura M. Kahn, The University of Texas MD Anderson Cancer Center
Allison M. Dyevoich PhD, The University of Texas MD Anderson Cancer Center
Josue Pineda, The University of Texas MD Anderson Cancer Center
Matthew C. Wong, The University of Texas MD Anderson Cancer Center
Aditya Mishra, The University of Texas MD Anderson Cancer Center
Samuel H. Cass, The University of Texas MD Anderson Cancer Center
Alexandria P. Cogdill, The University of Texas MD Anderson Cancer Center
Daniel Johnson, The University of Texas MD Anderson Cancer Center
Sarah B. Johnson, The University of Texas MD Anderson Cancer Center
Khalida Wani, The University of Texas MD Anderson Cancer Center
Debora A. Ledesma, The University of Texas MD Anderson Cancer Center
Courtney Hudgens, The University of Texas MD Anderson Cancer Center
Jingjing Wang, The University of Texas MD Anderson Cancer Center
Abdul Wadud Khan, The University of Texas MD Anderson Cancer Center
Christine B. Peterson, The University of Texas MD Anderson Cancer Center
Aron Y. Joon, The University of Texas MD Anderson Cancer Center
Weiyi Peng, The University of Texas MD Anderson Cancer Center
Haiyan S. Li, The University of Texas MD Anderson Cancer Center
Reetakshi Arora, The University of Texas MD Anderson Cancer Center
Ximing Tang, The University of Texas MD Anderson Cancer Center
Maria Gabriela Raso, The University of Texas MD Anderson Cancer Center
Xuegong Zhang, Tsinghua University
Wai Chin Foo, The University of Texas MD Anderson Cancer Center
Michael Tetzlaff, The University of Texas MD Anderson Cancer Center
Gretchen E. Diehl, Memorial Sloan Kettering Cancer Center
Karen Clise-Dwyer, The University of Texas MD Anderson Cancer Center
Elizabeth Whitley, The University of Texas MD Anderson Cancer Center
Matthew Gubin PhD, The University of Texas MD Anderson Cancer Center
James P. Allison, The University of Texas MD Anderson Cancer Center
Patrick Hwu, The University of Texas MD Anderson Cancer Center
Nadim Ajami, The University of Texas MD Anderson Cancer Center
Adi Diab, The University of Texas MD Anderson Cancer Center
Jennifer Wargo, The University of Texas MD Anderson Cancer Center
Stephanie S. Watowich PhD, The University of Texas MD Anderson Cancer Center

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Abstract

View full abstract

DOI

https://doi.org/10.52519/00101

Publication Date

2022

Department

Immunology

Research Category

Immune-Microbiome Biomarker Discovery

Recommended Citation

Zhou, Yifan; Medik, Yusra B.; Patel, Bhakti; Zamler, Daniel B.; Chen, Sijie; Chapman, Thomas; Schneider, Sarah; Park, Elizabeth M.; Babcock, Rachel; Chrisikos, Taylor; Kahn, Laura M.; Dyevoich, Allison M. PhD; Pineda, Josue; Wong, Matthew C.; Mishra, Aditya; Cass, Samuel H.; Cogdill, Alexandria P.; Johnson, Daniel; Johnson, Sarah B.; Wani, Khalida; Ledesma, Debora A.; Hudgens, Courtney; Wang, Jingjing; Khan, Abdul Wadud; Peterson, Christine B.; Joon, Aron Y.; Peng, Weiyi; Li, Haiyan S.; Arora, Reetakshi; Tang, Ximing; Raso, Maria Gabriela; Zhang, Xuegong; Foo, Wai Chin; Tetzlaff, Michael; Diehl, Gretchen E.; Clise-Dwyer, Karen; Whitley, Elizabeth; Gubin, Matthew PhD; Allison, James P.; Hwu, Patrick; Ajami, Nadim; Diab, Adi; Wargo, Jennifer; and Watowich, Stephanie S. PhD, "Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration" (2022). Leading Edge of Cancer Research Symposium. 56.
doi:https://doi.org/10.52519/00101