Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

Authors

• Yifan Zhou, The University of Texas MD Anderson Cancer Center
• Yusra B. Medik, The University of Texas MD Anderson Cancer Center
• Bhakti Patel, The University of Texas MD Anderson Cancer Center
• Daniel B. Zamler, The University of Texas MD Anderson Cancer Center
• Sijie Chen, Tsinghua University
• Thomas Chapman, The University of Texas MD Anderson Cancer Center
• Sarah Schneider, The University of Texas MD Anderson Cancer Center
• Elizabeth M. Park, The University of Texas MD Anderson Cancer Center
• Rachel Babcock, The University of Texas MD Anderson Cancer Center
• Taylor Chrisikos, The University of Texas MD Anderson Cancer Center
• Laura M. Kahn, The University of Texas MD Anderson Cancer Center
• Allison M. Dyevoich PhD, The University of Texas MD Anderson Cancer Center
• Josue Pineda, The University of Texas MD Anderson Cancer Center
• Matthew C. Wong, The University of Texas MD Anderson Cancer Center
• Aditya Mishra, The University of Texas MD Anderson Cancer Center
• Samuel H. Cass, The University of Texas MD Anderson Cancer Center
• Alexandria P. Cogdill, The University of Texas MD Anderson Cancer Center
• Daniel Johnson, The University of Texas MD Anderson Cancer Center
• Sarah B. Johnson, The University of Texas MD Anderson Cancer Center
• Khalida Wani, The University of Texas MD Anderson Cancer Center
• Debora A. Ledesma, The University of Texas MD Anderson Cancer Center
• Courtney Hudgens, The University of Texas MD Anderson Cancer Center
• Jingjing Wang, The University of Texas MD Anderson Cancer Center
• Abdul Wadud Khan, The University of Texas MD Anderson Cancer Center
• Christine B. Peterson, The University of Texas MD Anderson Cancer Center
• Aron Y. Joon, The University of Texas MD Anderson Cancer Center
• Weiyi Peng, The University of Texas MD Anderson Cancer Center
• Haiyan S. Li, The University of Texas MD Anderson Cancer Center
• Reetakshi Arora, The University of Texas MD Anderson Cancer Center
• Ximing Tang, The University of Texas MD Anderson Cancer Center
• Maria Gabriela Raso, The University of Texas MD Anderson Cancer Center
• Xuegong Zhang, Tsinghua University
• Wai Chin Foo, The University of Texas MD Anderson Cancer Center
• Michael Tetzlaff, The University of Texas MD Anderson Cancer Center
• Gretchen E. Diehl, Memorial Sloan Kettering Cancer Center
• Karen Clise-Dwyer, The University of Texas MD Anderson Cancer Center
• Elizabeth Whitley, The University of Texas MD Anderson Cancer Center
• Matthew Gubin PhD, The University of Texas MD Anderson Cancer Center
• James P. Allison, The University of Texas MD Anderson Cancer Center
• Patrick Hwu, The University of Texas MD Anderson Cancer CenterFollow
• Nadim Ajami, The University of Texas MD Anderson Cancer Center
• Adi Diab, The University of Texas MD Anderson Cancer Center
• Jennifer Wargo, The University of Texas MD Anderson Cancer Center
• Stephanie S. Watowich PhD, The University of Texas MD Anderson Cancer Center

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Abstract

View full abstract

DOI

https://doi.org/10.52519/00101

Publication Date

2022

Department

Immunology

Research Category

Immune-Microbiome Biomarker Discovery

Recommended Citation

Zhou, Yifan; Medik, Yusra B.; Patel, Bhakti; Zamler, Daniel B.; Chen, Sijie; Chapman, Thomas; Schneider, Sarah; Park, Elizabeth M.; Babcock, Rachel; Chrisikos, Taylor; Kahn, Laura M.; Dyevoich, Allison M. PhD; Pineda, Josue; Wong, Matthew C.; Mishra, Aditya; Cass, Samuel H.; Cogdill, Alexandria P.; Johnson, Daniel; Johnson, Sarah B.; Wani, Khalida; Ledesma, Debora A.; Hudgens, Courtney; Wang, Jingjing; Khan, Abdul Wadud; Peterson, Christine B.; Joon, Aron Y.; Peng, Weiyi; Li, Haiyan S.; Arora, Reetakshi; Tang, Ximing; Raso, Maria Gabriela; Zhang, Xuegong; Foo, Wai Chin; Tetzlaff, Michael; Diehl, Gretchen E.; Clise-Dwyer, Karen; Whitley, Elizabeth; Gubin, Matthew PhD; Allison, James P.; Hwu, Patrick; Ajami, Nadim; Diab, Adi; Wargo, Jennifer; and Watowich, Stephanie S. PhD, "Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration" (2022). Leading Edge of Cancer Research Symposium 2022. 56.
doi:https://doi.org/10.52519/00101