Chapter 06: Two-Hit Model Allows for Genetic Testing of Blood
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Description
Contributions: Dr. Knudson discusses how the two-hit model influenced research by opening the possibility of testing for the gene in patients' blood. He explains that this is useful for adults who had childhood cancer who want to know the likelihood of passing on the cancer to their children. Dr. Knudson mentions that the two-hit model additionally called attention and interest to other hereditary cancers.
Research Reflections: Dr. Knudson then reflects on the research process that led to the two-hit model, saying that he was lucky that retinoblastoma gave a quick answer to the problem.
Identifier
KnudsonA_01_20130305_C06
Publication Date
3-5-2013
Publisher
The Making Cancer History® Voices Oral History Collection, The University of Texas MD Anderson Cancer Center
City
Houston, Texas
Interview Session
Alfred G. Knudson, Jr., MD, PhD, Oral History Interview, March 05, 2013
Topics Covered
Contributions; The Researcher; Overview; Understanding Cancer, the History of Science, Cancer Research; Definitions, Explanations, Translations; On Research and Researchers
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Disciplines
History of Science, Technology, and Medicine | Oncology | Oral History
Recommended Citation
Knudson, Jr., Albert G. MD, PhD and Rosolowski, Tacey A. PhD, "Chapter 06: Two-Hit Model Allows for Genetic Testing of Blood" (2013). Interview Chapters. 304.
https://openworks.mdanderson.org/mchv_interviewchapters/304
Conditions Governing Access
Open
