Chapter 06: Two-Hit Model Allows for Genetic Testing of Blood

Title

Chapter 06: Two-Hit Model Allows for Genetic Testing of Blood

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Description

Contributions: Dr. Knudson discusses how the two-hit model influenced research by opening the possibility of testing for the gene in patients' blood. He explains that this is useful for adults who had childhood cancer who want to know the likelihood of passing on the cancer to their children. Dr. Knudson mentions that the two-hit model additionally called attention and interest to other hereditary cancers.

Research Reflections: Dr. Knudson then reflects on the research process that led to the two-hit model, saying that he was lucky that retinoblastoma gave a quick answer to the problem.

Identifier

KnudsonA_01_20130305_C06

Publication Date

3-5-2013

Publisher

The Making Cancer History® Voices Oral History Collection, The University of Texas MD Anderson Cancer Center

City

Houston, Texas

Topics Covered

Contributions; The Researcher; Overview; Understanding Cancer, the History of Science, Cancer Research; Definitions, Explanations, Translations; On Research and Researchers

Disciplines

History of Science, Technology, and Medicine | Oncology | Oral History

Conditions Governing Access

Open

Chapter 06: Two-Hit Model Allows for Genetic Testing of Blood

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