David J. Tweardy, MD, Oral History Interview, January 22, 2019
Files
Download Navigation Materials & Full Interview Transcript (1.2 MB)
Loading...
Description
Major Topics Covered:
- Personal background and education; spirituality; evolution of perspective on science and medicine
- Research: cytokines and shift to focus on oncology
Identifier
TweardyDJ_01_20190122
Publication Date
1-22-2019
Publisher
The Historical Resources Center, Research Medical Library, The University of Texas Cancer Center
City
Houston, Texas
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Topics Covered
University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Texas System. M.D. Anderson Cancer Center, M.D. Anderson Hospital and Tumor Institute at Houston, University of Texas M.D. Anderson Cancer Center, M.D. Anderson Hospital and Tumor Institute
Disciplines
History of Science, Technology, and Medicine | Oncology | Oral History
Recommended Citation
Tweardy, David J. MD and Rosolowksi, Tacey A. PhD, "David J. Tweardy, MD, Oral History Interview, January 22, 2019" (2019). Interview Sessions. 196.
https://openworks.mdanderson.org/mchv_interviewsessions/196
Conditions Governing Access
Open
About the Interview
About the Interview Subject
David J. Tweardy, MD (b. 12 February 1952, Charleroi, Pennsylvania) came to MD Anderson in 2014 to serve as head of the Division of Internal Medicine and join the faculty as a full professor in the Department of Infectious Diseases, Infection Control and Employee Health. At the time of the interview he also served as Department Chair ad interim for Department of Cardiology, Division of Internal Medicine. He has joint appointment in the Department of Molecular and Cellular Oncology in the Division of Basic Science Research, and in the Department of Department of Medicine, Section of Infectious Diseases, at the Baylor College of Medicine in Houston. His research includes: cytokine signaling and oncogenesis (structural and biochemical features of signaling proteins and oncoproteins that effect susceptibility to smallmolecule modulation); interactions of STAT3 and other oncoproteins with the major eukaryotic protein-folding machine; use of proteostasis modulators to improve the function of mutated David J. Tweardy, MD, Navigation Materials, p. 2 transcription factors that cause immunodeficiencies; contribution of STAT3 to infection- and inflammation-induced carcinogenesis; dtructure-based and high-throughput approaches to developing small-molecule inhibitors of STAT3; contribution of STAT3 to asthma and other allergic disorders.