Targeting Polo-Like Kinase 4 (PLK4) Triggers Polyploidy and Apoptosis in TP53-mutant Acute Myeloid Leukemia and Results in Improved Survival

Authors

• Akhil S. Marupudi, Texas A&M UniversityFollow
• Edward Ayoub PhD, The University of Texas MD Anderson Cancer Center
• Yuki Nishida MD, PhD, The University of Texas MD Anderson Cancer Center
• Wencke Walter PhD, Munich Leukemia Laboratory
• Torsten Haferlach MD, PhD, Munich Leukemia Laboratory
• Michael Andreeff MD, PhD, The University of Texas MD Anderson Cancer Center

Files

Keywords

AML; PLK4; P53; Apoptosis; Polyploidy

Program Affiliation

Summer Undergraduate Research Program

Recommended Citation

Marupudi, Akhil S.; Ayoub, Edward PhD; Nishida, Yuki MD, PhD; Walter, Wencke PhD; Haferlach, Torsten MD, PhD; and Andreeff, Michael MD, PhD, "Targeting Polo-Like Kinase 4 (PLK4) Triggers Polyploidy and Apoptosis in TP53-mutant Acute Myeloid Leukemia and Results in Improved Survival" (2022). Summer Experience 2022. 5.
https://openworks.mdanderson.org/sumexp22/5