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Leading Edge of Cancer Research Symposium

Leading Edge of Cancer Research Symposium: Poster Session

Over the past decade, cancer research has yielded a wealth of therapeutic options for patients for many different subtypes of cancer, as well as greater knowledge of this disease. Please see the symposium website for more details. View the poster collection below by Research Category:

Clinical Data Science

Clonal Expansion in Normal and Pathological Tissues:
It's All a Matter of Fitness

Integrated Immune-Microbiome Biomarker Discovery

The Patient is the Focus: Breakthroughs From Bench to Bedside,
Clinical and Multiomics Integration and High Value Cancer Care

Unleashing the Immune System to Develop Therapeutic Strategies

Other

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Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1 Mutant Myelodysplastic Syndromes With Ringed Sideroblasts

Vera Adema, Feiyang Ma, Rashmi Kanagal-Shamanna, Natthakan Thongon, Guillermo Montalban-Bravo, Hui Yang, Scott A. Peslak, Feng Wang, Pamela Acha, Francesc Sole, Pamela Lockyer, Margherita Cassari, Jaroslaw P. Maciejewski, Valeria Visconte, Irene Ganan-Gomez, Yuanbin Song, Carlos Bueso-Ramos, Matteo Pellegrini, Tuyet M. Tan, Rafael Bejar, Jennifer S. Carew, Stephanie Halene, Valeria Santini, Gheath Al Atrash, Karen Clise-Dwyer, Guillermo Garcia-Manero MD, Gerd A. Blobel, and Simona Colla

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Mitochondrial Respiration Regulates GPX4 Inhibition-Induced Ferroptosis in Acute Myeloid Leukemia

Hiroki Akiyama; Ran Zhao; Yuki Nishida MD, PhD; Lauren Ostermann; Po Yee Mak; Edward Ayoub PhD; Sujan Piya; Bing Z. Carter; Michael Andreeff MD, PhD; and Jo Ishizawa

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Aerobic exercise impacts the tumor microenvironment by altering CAF abundance and composition in pancreatic cancer

Riccardo Ballarò, Sumedha Pareek, Jonghae Lee, Hetal Patel, and Keri Schadler

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Long-term avasimibe treatment abolishes the breast cancer preventative efficacy of statin in a spontaneous mouse model of breast cancer

Rhea Bhala, Anjana Bhardwaj, Alexander Koh, Zhenlin Ju, Jing Wang, and Isabelle Bedrosian

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MOREHealth Research Group: more than clinical data!

Marina Borges and Luisa Lopes-Conceição

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Multi-disciplinary efforts to evaluate the therapeutic potential of CDK11, a novel transcription associated cyclin dependent kinase.

Christopher L. Carroll, Jan Reiling, Jeffrey Kovacs, Michael Bradley, Meng He, Nadima Uprety, Michael Peoples, Frederick Robinson, Alessandro Carugo, Michael Conner, Christian Rodriguez, Jennifer Bardenhagen, Vijayan Ramaswamy, Paul Leonard, Zhijun Kang, Catalina Suarez, Teresa Perry, Jing Han, Sonal Fnu, Nakia D. Spencer, Guang Gao, Angela Harris, Alan Xu, Jennifer Linares, Thomas M. Quill, Phuong Nguyen, Qi Wu, Stephanie T. Schmidt PhD, Sahil Seth, Christopher A. Bristow, Norma Rogers, Simon S. Yu, Hannah E. Shepard, Robert A. Mullinax, Sabina A. Lorca, Kang Le, Reagan Lucas, Sweta Mahaeshwari, Sarah Joseph, Ningping Feng, Yongying Jiang, Joe Marszalek, Michael Soth, Jason Cross, Mary Geck Do, M. Emilia Di Francesco, Timothy P. Heffernan, and Philip Jones

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Ether phospholipids metabolism is a latent vulnerability for pancreatic cancer resistance

Ziheng Chen; I-Lin Ho; Liang Yan; Shujuan Chen; Melinda Soeung; Johnathon L. Rose; Sanjana Srinivasan; Andrea Viale; Alessandro Carugo; Giannicola Genovese; Wantong Yao MD, PhD; Ningping Feng; Jason P. Gay; Joeeph Marszalek; Haoqiang Ying; and Giulio Draetta

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Transcriptional profiling and consensus molecular subtype (CMS) assignment to understand response and resistance to anti-EGFR therapy in colorectal cancer

Saikat Chowdhury, Ria Gupta, Valsala Haridas, Mohammad Zeineddine, Scott Kopetz, and John Paul Shen

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DPY30 loss leads to DNA re-replication and immunoediting in pancreatic ductal adenocarcinoma

Francesca Citron, Luigi Perelli, Yanshuo Chu, Sanjana Srinivasan, I-Lin Ho, Er-Yen Yen, Rutvi Shah, Sergio Attanasio, Luis Alejandro Castillo Montanez, Mauro Di Pilato, Shan Jiang, Sisi Gao, Angela K. Deem, Giannicola Genovese, Virginia Giuliani, Linghua Wang, Alessandro Carugo, Andrea Viale, and Giulio Draetta

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Clinical and Environment Factors Impacting Malignant Pleural Mesothelioma Prognosis

Nathaniel Deboever, Daniel McGrail, Nicolas Zhou, Mehmet Altan, Jacqueline Olivia, Edwin Parra, Jianjun Zhang, Percy P. Lee, Ravi Rajaram, Wayne Hofstetter, Ara Vaporciyan, Reza J. Mehran, David C. Rice, Katarzyna Tomczak, Annikka Weissferdt, Anne S. Tsao, Cara Haymaker, and Boris Sepesi

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Organoid Imaging Strategies for Accelerating Translational Research

Charles Deckard III, Joseph R. Daniele, Dmitriy Loza, Vandhana Ramamoorthy, Kuo-Shun Hsu, Mikhila Mahendra, Ben Bivona, Ningping Feng, Henry Lyu, Jing Han, and Joe Marszalek

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Probabilistic Segmentation of Small Metastatic Brain Tumors using Liquid State Machine Ensemble

Andrew Elliott, Cole Morgan, Carlo Torres, Ayman Roslend, and Caroline Chung MD

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Retrospective Determination of Prognostic Factors in BRAF-V600E Melanoma Brain Metastases

Lily G. Erickson BS, Sahana Ramaswamy, Sherise D. Ferguson, James P. Long PhD, Hussein Tawbi, Merve Hasanov, Alicia B. Davies, Elizabeth Sirmans, Chantal Saberian, Eliza L. Posada, Jared Malke, Lauren Haydu, and Caroline Chung MD

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Galectin-3 synergizes with CD47 to Suppress Phagocytosis and T cell immunity in Peritoneal Metastases of Gastric Adenocarcinoma

Yibo Fan, Shilpa S. Dhar, Jiankang Jin, Xiaodan Yao, Ruiping Wang, Ailing W. Scott, Melissa Pool Pizzi, Lang Ma, Shan Shao, Matheus Sewastjanow Da Silva, Jingjing Wu, Namita Shanbhag, Linghua Wang, Michael Curran, Shumei Song, and Jaffer A. Ajani

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Immune microenvironment dysfunctions enable malignification at the onset of myelodysplastic syndromes

Irene Ganan-Gomez; Feiyang Ma; Kelly S. Chien; Hui Yang; Guillermo Montalban-Bravo; Bethany E. Wildeman; Bijender Kumar; Yi June Kim; May Daher; Koichi Takahashi MD, PhD; Guillermo Garcia-Manero MD; and Simona Colla

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Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease

Eiko Hayase, Tomo Hayase, Mohamed A. Jamal, Takahiko Miyama, Chia-Chi Chang, Miriam R. Ortega, Saira S. Ahmed, Jennifer L. Karmouch, Christopher A. Sanchez, Alexandria N. Brown, Rawan K. El-Himri, Ivonne I. Flores, Lauren K. McDaniel, Dung Pham, Taylor Halsey, Annette C. Frenk, Valerie A. Chapa, Brooke E. Heckel, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Lin Tan, Lucas Veillon, Nadim Ajami, Jennifer Wargo, Jessica Galloway-Peña, Samuel Shelburne, Roy F. Chemaly, Lauren Davey, Robert WP Glowacki, Chen Liu, Gabriela Rondon, Amin M. Alousi, Jeffrey Molldrem, Richard Champlin, Elizabeth Shpall MD, Raphael H. Valdivia, Eric C. Martens, Philip L. Lorenzi, and Robert R. Jenq

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Clonal dominance defines metastatic dissemination in pancreatic cancer

I-Lin Ho, Chieh-Yuan Li, Fuchenchu Wang, Li Zhao, Jingjing Liu, Er-Yen Yen, Yanshuo Chu, Francesca Citron, Rutvi Shah, Sergio Attanasio, Melinda Soeung, Ziheng Chen, Jiang Hong, Jiang Shan, Sisi Gao, Angela K. Deem, Andrew Futreal, Haoqiang Ying, Giannicola Genovese, Jianhua Zhang, Anirban Maitra, Timothy P. Heffernan, Linghua Wang, Giulio Draetta, Kim-Anh Do, Alessandro Carugo, Ruitao Liu, and Andrea Viale

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Comparative Transcriptomic Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors

Eleonora Khlebus, Veena K. Vuttaradhi, Thomas Welte, Namrata Khurana, Joseph Celestino, Hannah C. Beird, Curtis Gumbs, Latasha Little, Tri Nguyen, Barrett Lawson, Russell R. Broaddus, David M. Gershenson MD, Andrew Futreal, and R Tyler Hillman

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Utility of gross tumor palpability or tumor size as a measure of drug efficacy for cancer prevention

Alexander Koh, Anjana Bhardwaj, Matthew D. Embury, Raniv D. Rojo, and Isabelle Bedrosian

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Role of HIF2 signaling in small intestine regeneration after radiation injury

Neeraj Kumari; Maya Ferrell; Carolina Garcia-Garcia; and Cullen M. Taniguchi MD, PhD

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Therapeutic Potential of Ralimetinib, a p38/MAPK14 Inhibitor, in Anaplastic Thyroid Cancer

Muthusamy Kunnimalaiyaan, Ali Dadbin, Ying Henderson, Elena McBeath Fujiwara, Clifford Stephan, Roza Nurieva PhD, Naifa L. Busaidy, Jennifer R. Wang, Stephen Lai, Maria Cabanillas, Marc E. Zafereo, Ramona Dadu, and Marie-Claude Hofmann

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Improving Healthcare Access: Using an Ontology Platform to Connect Bronchial-Associated Lymphoid Tissue Patients with COVID-19 to Clinical Trials

Yan Leyfman, Samarth Sandeep, Kirk McGregor, and Chandler H. Park

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Tackling Healthcare Inequities: Development & Implementation of a Virtual Platform to Improve Global Access to Oncology Education

Yan Leyfman, William B. Wilkerson, Shubhadarshini G. Pawar, Muskan Joshi, Gayathri Pramil Menon, Alexandra van de Kieft, and Chandler H. Park

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Histone demethylase KDM5D drives sex-specific differences in colorectal cancer

Jiexi Li; Zhengdao Lan; Wenting Liao; James W. Horner; Xueping Xu; Jielin Liu; Yohei Yoshihama; Shan Jiang; Hong Seok Shim; Max Slotnik; Chang-Jiun Wu; Kenneth Dunner, Jr.; Rumi Lee; Isha Khanduri; Christopher Terranova; Kadir Caner Akdemir; Deepavali Chakravarti; Kyle LaBella; Wen-Hao Hsu; Denise J. Spring; Y. Alan Wang; and Ronald A. DePinho

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Targeting histone lysine demethylase KDM4A in Aggressive Variant Prostate Cancer

Celia Sze Ling Mak, Ming Zhu, Xin Liang, Feng Wang, Anh G. Hoang, Xinzhi Song, Peter Shepherd, Derek Liang, Jessica Suh, Jiwon Park, Miao Zhang, Eric Metzger, Roland Schule, Abhinav K. Jain, Ellen Karasik, Barbara A. Foster, Min Gyu Lee, Paul Corn, Christopher J. Logothetis MD, Ana Aparicio, Nora Navone, Patricia Troncoso, Jianhua Zhang, Sue-Hwa Lin, and Guocan Wang

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Skin Cancers in Patients with Actinic Keratoses

Cassandra Mohr, Yao Li, Lucy J. Navsaria, Candice L. Hinkston, and Mackenzie R. Wehner

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Loss of BRD7 promotes breast cancer lung metastasis by reprogramming the tumor immune microenvironment

Jayanta Mondal; Junfeng Zhang; Filippo G. Giancotti MD, PhD; and Jason Huse

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The role of different microbiota in metastatic brain tumors

Golnaz Morad, Ashish Damania, Matthew Wong, Sarah Johnson, Pranoti Sahasrabhojane, Nadim Ajami, Sherise D. Ferguson, and Jennifer Wargo

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Enhanced TP53 Reactivation Disrupts MYC Transcriptional Program and Overcomes Venetoclax Resistance in Acute Myeloid Leukemias

Yuki Nishida MD, PhD; Jo Ishizawa; Edward Ayoub PhD; Tallie Patsilevas; Lauren Ostermann; Rafael Heinz Montoya; Muharrem Muftuoglu; Vivian R. Ruvolo; Po Yee Mak; Wenjing Tao; Bing Z. Carter; Darah A. Scruggs; Kensuke Kojima; Naval Daver; Takahiko Seki; Sharon Shacham; Marina Konopleva MD, PhD; and Michael Andreeff MD, PhD

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C-MYC Targeting by Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Exerts Profound Cell Kill in vitro and in vivo in Acute Myeloid Leukemia and Lymphomas

Yuki Nishida MD, PhD; Darah A. Scruggs; Edward Ayoub PhD; Tallie Patsilevas; Lauren Ostermann; Vivian R. Ruvolo; Po Yee Mak; Bing Z. Carter; Steffen Boettcher; Abhishek Maiti; Qianxiang Zhou; Zhaohui Yang; Honghua Yan; Liandong Ma; and Michael Andreeff MD, PhD

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Characterization of Altered immunity in Anaplastic Thyroid Cancer

Rim Ouni PhD; Ying Henderson; Yunyun Chen; Naimah Turner; William Padron; Ali Dadbin; Elena McBeath Fujiwara; Jennifer R. Wang; Maria Cabanillas; Ramona Dadu; Marie-Claude Hofmann; MarK E. Zafereo; Sang Taek Kim MD, PhD; Stephen Lai; and Roza Nurieva PhD

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IL-6 contributes to the suppression of T and NK cell anti-tumor activity in EGFR-mutant NSCLC

Sonia A. Patel, Monique B. Nilsson, Yan Yang, XIaoxing Yu, Fahao Zhang, Alissa Poteete, Xiaoyang Ren, Xiuning Le, Li Shen, Jing Wang, and John Heymach

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Convergent evolutionary trajectories uncover metastatic drivers in renal cancer

Luigi Perelli, Li Zhang, Courtney N. Le, Francesca Citron, Melinda Soeung, Sebastian Lundgren, Hania Khan, Linghua Wang, Pavlos Msaouel, Giulio Draetta, Ari Hakimi, Alessandro Carugo, and Giannicola Genovese

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K811 acetylation regulates ZEB1 dimerization, protein stability, and NuRD complex interactions to promote lung adenocarcinoma progression and metastasis

Mabel Perez-Oquendo, Roxsan Manshouri, Jared J. Fradette, and Don Gibbons

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Use of proton pump inhibitors and risk of gastric cancer

Daniele Piovani PhD, Andreas Tsantes, and Stefanos Bonovas

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Targeting immunosuppressive classical monocytes prevents immunotherapy resistance

B. Leticia Rodriguez, Limo Chen, Yanli Li, Shucheng Miao, David H. Peng, Jared Fradette, Lixia Diao, Jessica Marie Konen, Aparna Padhye, Laura Gibson, Joshua K. Ochieng, Xiaofei Zhou PhD, Jing Wang, and Don Gibbons

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Characterizing the role of chromosome 3 copy-loss in driving late-stage Uveal Melanoma

Johnathon L. Rose, Sanjana Srinivasan, and The Rare Tumor Initiative Team and TRACTION Platform

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Impact of Salvage Surgery and Re-irradiation for Radiation Failed Recurrent Skull Base Meningiomas

Franco Rubino, Solon Schur, Susan L. McGovern, Carlos Kamiya-Matsuoka, Franco DeMonte, and Shaan M. Raza

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Characterization of T/B cell antigen specific-engineered tumors for studying T cell and GC B cell function in a murine model of NSCLC

Armando J. Ruiz-Justiz; Mona Yazdani; Xin Sun; Lili Chen; Michael Wang; John Le; Haiping Guo; Can Cui; Kelli Cannolly; Aya Tal; Wei Hu MD, PhD; Nikhil Joshi PhD; and Tina Cascone MD, PhD

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Long-term outcomes after haploidentical stem cell transplantation (haplo-SCT) for hematologic malignancies

Supawee Saengboon, Jeremy Ramdial, Neeraj Saini, Amanda Olson, Jin Im, Chitra Hosing, Uday Popat, Elizabeth Shpall MD, Richard Champlin, and Samer A. Srour

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Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set

Stephanie T. Schmidt PhD, Neal Akhave, Ryan Knightly, Alexandre Reuben, Natalie Vokes, Jianhua Zhang, Jun Li, Junya Fujimoto, Lauren A. Byers, Beatriz Sanchez-Espiridion, Lixia Diao, Jing Wang, Lorenzo Federico, Marie-Andree Forget, Daniel McGrail, Annikka Weissferdt, Shiaw-Yih Lin, Younghee Lee, Erika Suzuki, Jeffrey Kovacs, Carmen Behrens, Ignacio Wistuba, Andrew Futreal, Ara Vaporciyan, Boris Sepesi, John Heymach, Chantale Bernatchez, Cara Haymaker, Tina Cascone, Jianjun Zhang, Christopher A. Bristow, Timothy P. Heffernan, Marcelo V. Negrao, Don Gibbons, and ICON team

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VirMAP for Cancer: Characterization of the Intratumoral Virome in Virally-Associated Cancers and a Resource for Investigators

Y David Seo, Neal Bhutiani, Matthew Wong, Matthew Lastrapes, Alexander Lazar, Florencia McAllister, Lauren Colbert MD, Ann H. Klopp, Sherise D. Ferguson, Frederick Lang, Jennifer Wargo, and Nadim Ajami

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Cancer testis antigen and interleukin expression correlates with survival in small bowel neuroendocrine tumors

Y David Seo, Russell G. Witt, Samuel Cass, Rossana Lazcano, Courtney Hudgens, Khalida Wani, Sharia Hernandez, Daniel Halperin, Alexander Lazar, Jennifer Wargo, Jeannelyn S. Estrella, and Jessica E. Maxwell

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SMARCB1 regulates the hypoxic stress response in sickle cell trait during the pathogenesis of renal medullary carcinoma.

Melinda Soeung, Luigi Perelli, Ziheng Chen, Eleonora Dondossola, I-Lin Ho, Federica Carbone, Michael Peoples, Ningping Feng, Rosalba Minelli, Cihui Zhu, Courtney N. Le, Hania Khan, Shan Jiang, Daniel D. Shapiro, Angela K. Deem, Sisi Gao, Emily H. Cheng, Cheryl L. Walker PhD, Alessandro Carugo, Timothy P. Heffernan, Andrea Viale, Nizar M. Tannir, Giulio Draetta, Pavlos Msaouel, and Giannicola Genovese

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Development of a Novel Combination Therapy targeting MET and LGR5 to overcome Colorectal Cancer Resistance

Shraddha Subramanian, Tressie Posey, Joan Jacob, and Kendra S. Carmon

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Determine the relevance of HPV-specific T-cells in the immune response against the HPV-positive cancers

Klaudia A. Szymonowicz, Emily G. Bontekoe, Bo Jiang, Alexa J. Halliday, Maura Gillison L, and Nils-Petter Rudqvist

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Inactivation of Aurora kinases and Cyclin-dependent kinases 4/6 allows cancers to adopt an endoreplication and form polyploid/polyaneuploid giant cancer cells (PGCCs/PACCs) that resist antimitotic drugs

Vural Tagal, Uttam K. Tambar, Noemi Andor, Michael G. Roth, and John D. Minna

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The impact of targeting TRAF2 and NCK-interacting protein kinase (TNIK) on anti-tumor effect in small cell lung cancer

Azusa Tanimoto, Ben Morris, Kavya Ramkumar, Robert Cardnell, Shen Li, Qi Wang, Allison Stewart, Carl Gay, Jing Wang, and Lauren A. Byers

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Targeting DNA2 Overcomes Metabolic Reprogramming in 1q21 Multiple Myeloma

Natthakan Thongon; Feiyang Ma; Matteo Marchesini; Jintan Liu; Natalia Baran; Pamela Lockyer; Andrea Santoni; Christopher Jackson; Ashley Rose; Irene Ganan-Gomez; Vera Adema; Valentina Marchica; Paola Storti; Nicola Giuliani; Guillermo Montalban-Bravo; Yun Qing; Min Ha; Rodrigo Fonseca; Caleb Class; Lin Tan; Rashmi Kanagal-Shamanna; David Berrios Nolasco; Marina Konopleva MD, PhD; Philip L. Lorenzi; Guillermo Garcia-Manero MD; Elisabet Manasanch; Marta Chesi; and Simona Colla

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Unraveling the Biology of Desmoplastic Small Round Cell Tumor

Danh D. Truong, Emre Arslan, Margarita Divenko, Sandhya Krishnan, Alexander Lazar, Kunal Rai, and Joseph Ludwig

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Oncogenic Foxl2 is a chromatin-remodeling pioneer transcription factor in adult-type ovarian granulosa cell tumors

Veena K. Vuttaradhi, Eleonora Khlebus, Thomas Welte, Namrata Khurana, and R Tyler Hillman

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Lysosomal transmembrane protein TMEM106B alters TFEB signaling and the tumor immune microenvironment

Amanda N. Warner, Samrat T. Kundu, Rakhee Bajaj, Bertha Leticia Rodriguez, and Don Gibbons

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Exploring anti-PD-1 resistance mechanisms for therapeutic targeting in NSCLC

Haoyi Wu, Jessica Marie Konen, Leticia Rodriguez, Yanhua Tian, Susan Tsang, Jared Fradette, Laura Gibson, and Don Gibbons

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Utility of plasma tumor marker levels in management of patients with appendiceal adenocarcinoma

Abdelrahman M. Yousef, Aditya More, Mohammad Zeineddine, Saikat Chowdhury, Yue Gu, Julia Dansby, Zahra Alavi Naini, Abhineet Uppal, Kanwal Raghav, Michael J. Overman, Keith Fournier, and John Paul Shen

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Goblet Cell Tumors of the Appendix: Clinical & Molecular Features

Abdelrahman M. Yousef, Zahra Alavi Naini, Mohammad Zeineddine, Saikat Chowdhury, Julia Dansby, Aditya More, Abhineet Uppal, Kanwal Raghav, Michael J. Overman, Keith Fournier, and John Paul Shen

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A Prospective Randomized Crossover Trial of Systemic Chemotherapy in Patients with Low-Grade Mucinous Appendiceal Adenocarcinoma

Abdelrahman M. Yousef, John Paul Shen, Fadl Zeineddine, Mohammad Zeineddine, Becky Slack Tidwell, Robert A. Wolff, Aurelio Matamoros, Wai Chin Foo, Melissa Taggart, Abhineet Uppal, Christopher Scally, Paul Mansfield, Safia Rafeeq, Kanwal Raghav, Michael J. Overman, and Keith Fournier

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Targeting Medium-Chain Acyl-CoA Dehydrogenase for Glioblastoma

Fei Yu, Paul Leonard, Matthew Hamilton, Francesca Puca, Nhung Pham, Norma Rogers, Fernando Alvarez, C Rodriguez, Vinay Nair, Narahari Akkaladevi, Roopa Thapar, Scott Vaccaro, Andrea Mendiola, Quanyun Xu, Mary Geck Do, Jason Cross, Mick Soth, Yongying Jiang, Giulio Draetta, and Philip Jones

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Validating DLL3-targeting CAR T in small cell lung cancer

Bingnan Zhang, Yan Yang, Allison Stewart, Runsheng Wang, Kavya Ramkumar, Robert Cardnell, Azusa Tanimoto, Ali Ibraham, Kyle Concannon, Ben Morris, Lixia Diao, Qi Wang, Jing Wang, Carl Gay, John Heymach, and Lauren A. Byers

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Efficacy and immune modulation of KRAS G12C inhibitor sotorasib in murine KRAS G12C mutant non-small cell lung cancers with major co-occurring genomic alterations

Teng Zhou, Minh Truong Do, Haniel Araujo, Richard Lee, and Ferdinandos Skoulidis

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Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration

Yifan Zhou, Yusra B. Medik, Bhakti Patel, Daniel B. Zamler, Sijie Chen, Thomas Chapman, Sarah Schneider, Elizabeth M. Park, Rachel Babcock, Taylor Chrisikos, Laura M. Kahn, Allison M. Dyevoich PhD, Josue Pineda, Matthew C. Wong, Aditya Mishra, Samuel H. Cass, Alexandria P. Cogdill, Daniel Johnson, Sarah B. Johnson, Khalida Wani, Debora A. Ledesma, Courtney Hudgens, Jingjing Wang, Abdul Wadud Khan, Christine B. Peterson, Aron Y. Joon, Weiyi Peng, Haiyan S. Li, Reetakshi Arora, Ximing Tang, Maria Gabriela Raso, Xuegong Zhang, Wai Chin Foo, Michael Tetzlaff, Gretchen E. Diehl, Karen Clise-Dwyer, Elizabeth Whitley, Matthew Gubin PhD, James P. Allison, Patrick Hwu, Nadim Ajami, Adi Diab, Jennifer Wargo, and Stephanie S. Watowich PhD

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Yap1 Hydroxylation Suppress Prostate Cancer Metastasis

Ming Zhu, Ruiqing Peng, Xin Liang, Zhengdao Lan, Ming Tang, Pingping Hou, Jian H. Song, Celia Sze Ling Mak, Jiwon Park, Shui-Er Zheng, Ailing Huang, Xingdi Ma, Ruidong Chen, Qing Chang, Christopher J. Logothetis MD, Abhinav K. Jain, Sue-Hwa Lin, Hiroyuki Katayama, Samir Hanash, and Guocan Wang

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